{"id":310198,"date":"2022-01-11T11:59:00","date_gmt":"2022-01-11T11:59:00","guid":{"rendered":"https:\/\/afrikmag.com\/var\/www\/vhosts\/afrikmag.compublic_html\/?p=310198"},"modified":"2022-01-11T11:59:13","modified_gmt":"2022-01-11T11:59:13","slug":"coeur-porc-transplante-americain-chirurgie-revolutionnaire","status":"publish","type":"post","link":"https:\/\/afrikmag.com\/var\/www\/vhosts\/afrikmag.compublic_html\/coeur-porc-transplante-americain-chirurgie-revolutionnaire\/","title":{"rendered":"Le c\u0153ur d\u2019un porc transplant\u00e9 chez un Am\u00e9ricain lors d’une chirurgie r\u00e9volutionnaire"},"content":{"rendered":"\n

Les chirurgiens du centre m\u00e9dical de l’Universit\u00e9 du Maryland ont effectu\u00e9 la premi\u00e8re proc\u00e9dure du genre sur un r\u00e9sident du Maryland identifi\u00e9 comme David Bennett.<\/p>\n\n\n\n

L’homme de 57 ans qui n’avait plus d’options est devenu le premier receveur d’un c\u0153ur de porc g\u00e9n\u00e9tiquement modifi\u00e9. Bennett a \u00e9t\u00e9 diagnostiqu\u00e9 avec une maladie cardiaque en phase terminale et avait \u00e9t\u00e9 hospitalis\u00e9 et alit\u00e9 pendant plusieurs semaines apr\u00e8s avoir \u00e9t\u00e9 \u00ab\u00a0jug\u00e9 in\u00e9ligible\u00a0\u00bb pour une transplantation cardiaque traditionnelle.<\/p>\n\n\n\n

Le patient a d\u00e9clar\u00e9 dans un communiqu\u00e9 publi\u00e9 par le centre m\u00e9dical de l’Universit\u00e9 du Maryland: \u00ab C’\u00e9tait soit mourir, soit faire cette greffe. Je veux vivre. Je sais que c’est un coup dans le noir, mais c’est mon dernier choix. J’ai h\u00e2te de sortir du lit apr\u00e8s avoir r\u00e9cup\u00e9r\u00e9.\u00a0\u00bb<\/em><\/p>\n\n\n\n

La Food and Drug Administration des \u00c9tats-Unis a accord\u00e9 une autorisation d’urgence pour la chirurgie en vertu de sa disposition d’utilisation compassionnelle le soir du Nouvel An. <\/p>\n\n\n\n

Les chercheurs ont d\u00e9clar\u00e9 que la proc\u00e9dure a n\u00e9cessit\u00e9 10 modifications g\u00e9n\u00e9tiques uniques du c\u0153ur de porc afin d’emp\u00eacher le rejet de l’organe une fois transplant\u00e9 dans le corps humain. Ces modifications comprenaient la suppression de quatre des g\u00e8nes de l’animal responsables du rejet d’organes de porc par les anticorps de l’homme, ainsi que l’insertion de six g\u00e8nes humains dans le g\u00e9nome pour l’acceptation immunitaire.<\/p>\n\n\n\n

\"Le<\/a><\/figure>\n\n\n\n

Le Dr Bartley Griffith, qui a pratiqu\u00e9 l’op\u00e9ration, a d\u00e9clar\u00e9 dans un communiqu\u00e9: \u00ab\u00a0Il s’agissait d’une op\u00e9ration chirurgicale r\u00e9volutionnaire qui nous rapproche un peu plus de la r\u00e9solution de la crise de la p\u00e9nurie d’organes. Il n’y a tout simplement pas assez de c\u0153urs humains de donneurs disponibles pour r\u00e9pondre \u00e0 la longue liste de receveurs potentiels. Nous proc\u00e9dons avec prudence, mais nous sommes \u00e9galement optimistes quant au fait que cette premi\u00e8re intervention chirurgicale au monde offrira une nouvelle option importante pour les patients \u00e0 l’avenir.\u00a0\u00bb<\/em><\/p>\n\n\n\n

\"Le<\/figure>\n\n\n\n

Trois jours apr\u00e8s l’op\u00e9ration, le centre m\u00e9dical universitaire a d\u00e9clar\u00e9 lundi 10 janvier que Bennett se portait bien et qu’il continuerait \u00e0 \u00eatre surveill\u00e9 dans les semaines \u00e0 venir pour s’assurer que l’organe n’est pas rejet\u00e9.<\/p>\n\n\n\n

LIRE AUSSI: \u00c9tats-Unis \/ un rein de porc transplant\u00e9 dans un humain : une premi\u00e8re dans l\u2019histoire<\/a><\/p>\n\n\n\n

Il est toujours connect\u00e9 \u00e0 une machine de pontage c\u0153ur-poumon, mais le nouveau c\u0153ur fonctionne et assume la majorit\u00e9 du travail pour son corps, ont d\u00e9clar\u00e9 les chirurgiens au New York Times.<\/p>\n\n\n\n

Bennett pourrait \u00eatre retir\u00e9 de la machine de d\u00e9rivation d\u00e8s le mardi 11 janvier, si tout se passe bien, ont d\u00e9clar\u00e9 ses m\u00e9decins.<\/p>\n","protected":false},"excerpt":{"rendered":"

Les chirurgiens du centre m\u00e9dical de l’Universit\u00e9 du Maryland ont effectu\u00e9 la premi\u00e8re proc\u00e9dure du genre sur un r\u00e9sident du Maryland identifi\u00e9 comme David Bennett. L’homme de 57 ans qui n’avait plus d’options est devenu le premier receveur d’un c\u0153ur de porc g\u00e9n\u00e9tiquement modifi\u00e9. Bennett a \u00e9t\u00e9 diagnostiqu\u00e9 avec une maladie cardiaque en phase terminale …<\/p>\n","protected":false},"author":37,"featured_media":310206,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[189118,8766,46],"tags":[2451,170393,2284],"class_list":["post-310198","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-a-la-une","category-monde","category-usa","tag-chirurgie","tag-coeur-2","tag-porc"],"yoast_head":"\nLe c\u0153ur d\u2019un porc transplant\u00e9 chez un Am\u00e9ricain lors d'une chirurgie r\u00e9volutionnaire<\/title>\n<meta name=\"description\" content=\"L'homme de 57 ans qui n'avait plus d'options est devenu le premier receveur r\u00e9ussi d'un c\u0153ur de porc g\u00e9n\u00e9tiquement modifi\u00e9.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link 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